The graph below ranks each Mississippi County by total residents according to the 2006 census estimates.
Mississippi total population by county
| County | Total Population |
| Hinds |  249,012 |
| Harrison | 171,875 |
| DeSoto | 144,706 |
| Rankin | 135,830 |
| Jackson | 130,577 |
| Madison | 87,419 |
| Lee | 79,714 |
| Lauderdale | 76,724 |
| Forrest | 76,372 |
| Jones | 66,715 |
| Lowndes | 59,773 |
| Washington | 58,007 |
| Pearl River | 57,099 |
| Warren | 49,308 |
| Lamar | 46,240 |
| Oktibbeha | 41,633 |
| Lafayette | 40,865 |
| Hancock | 40,421 |
| Pike | 40,240 |
| Bolivar | 38,352 |
| Monroe | 37,572 |
| Marshall | 35,853 |
| Leflore | 35,752 |
| Alcorn | 35,589 |
| Panola | 35,427 |
| Lincoln | 34,404 |
| Adams | 32,626 |
| Sunflower | 31,833 |
| Neshoba | 30,125 |
| Copiah | 29,223 |
| Pontotoc | 28,887 |
| Scott | 28,790 |
| Coahoma | 28,420 |
| Simpson | 27,972 |
| Yazoo | 27,929 |
| Union | 27,008 |
| Tate | 26,723 |
| Marion | 25,730 |
| Prentiss | 25,615 |
| Itawamba | 23,352 |
| Grenada | 22,861 |
| Leake | 22,769 |
| Newton | 22,413 |
| George | 21,828 |
| Tippah | 21,248 |
| Clay | 21,210 |
| Wayne | 21,087 |
| Holmes | 20,866 |
| Covington | 20,447 |
| Winston | 19,708 |
| Attala | 19,644 |
| Tishomingo | 19,112 |
| Chickasaw | 18,998 |
| Jasper | 18,197 |
| Clarke | 17,631 |
| Smith | 15,970 |
| Stone | 15,608 |
| Walthall | 15,543 |
| Calhoun | 14,647 |
| Tallahatchie | 13,798 |
| Amite | 13,466 |
| Lawrence | 13,457 |
| Yalobusha | 13,401 |
| Jefferson Davis | 13,184 |
| Greene | 13,103 |
| Perry | 12,132 |
| Noxubee | 12,051 |
| Montgomery | 11,754 |
| Claiborne | 11,487 |
| Tunica | 10,419 |
| Humphreys | 10,393 |
| Carroll | 10,326 |
| Wilkinson | 10,239 |
| Kemper | 10,108 |
| Webster | 10,041 |
| Choctaw | 9,401 |
| Quitman | 9,289 |
| Jefferson | 9,194 |
| Franklin | 8,269 |
| Benton | 7,873 |
| Sharkey | 5,851 |
| Issaquena | 1,805 |